Bizorn OMEGAS®

This synergistic combination of powerful, clinically validated ingredients:*

• Reduces hard-to-lose visceral fat by 22% in 60 days
• Can help you lose up to 30 pounds in 90 days
• Reduces body mass index (BMI) by up to 13.9%
• Can help shrink your waistline by up to 10.7%
• Helps suppress appetite and promotes satiety
• Reduces insulin resistance in as little as 30 days
• Reduces fasting insulin levels by 42% in 60 days
• Promotes metabolic health and blood sugar balance
• Supports healthy cholesterol and triglyceride levels

General Product Info:

• 60 vegetarian capsules (a 30 day supply)
• Made in the USA in an FDA inspected, cGMP facility
• Every batch is 3rd party tested for safety and purity
• Packaged in premium, non-toxic amber glass bottles
• One-year return policy with free return shipping

While berberine only recently began “trending,” Dr. Passero has been using it in his clinic for over two decades to help patients optimize their metabolic health for healthy, permanent weight loss, and natural blood sugar and cholesterol control. This 20+ years of experience went into formulating Bizorn BERBERINE, which features a potent 1,100 mg daily dose of a standardized, highly absorbable berberine extract called Berbevis®. Widely recognized as one of the best berberine extracts in the world, this phytosome-form extract utilizes an innovative delivery system to provide up to 10x better absorption than the berberine extracts found in most supplements.*

Berberine’s powerful weight loss promoting, metabolic boosting and blood sugar balancing effects are synergistically enhanced with 300 mg of clinically studied, caffeine-free Greenselect® green tea extract and a therapeutic 200 mcg dose of Albion® chromium for even greater benefits.*

What Is Berberine and How Does It Work?
Berberine is an extraordinarily powerful plant alkaloid found in some of nature’s most revered medicinal herbs, including barberry, goldenseal and Oregon grape root. Extensive scientific research shows that, among a slew of health benefits, berberine excels at promoting blood sugar balance—and weight loss—via its regulating effects on metabolism.*

Berberine activates an energy-stabilizing enzyme called AMPK, often referred to as the “metabolic master switch,” which helps maintain balanced blood sugar levels and overall metabolic health. In addition, berberine enhances insulin sensitivity, which means it helps cells respond more effectively to the hormone insulin that controls blood sugar levels. This can lead to better regulation of blood sugar, better appetite control and reduced fat storage.*

Recently, berberine has soared in popularity, due to its “side effect” of promoting healthy weight loss via its actions on blood sugar and metabolism.*

Berberine’s weight loss benefits may also be related to its ability to increase metabolic rate and influence the activity of genes and enzymes involved in fat metabolism. In addition, some studies suggest that berberine may impact hormones involved in appetite regulation, including ghrelin, a hormone that stimulates hunger, and leptin, a hormone that signals satiety.*

Berberine also helps reduce inflammation and promotes a healthy gut microbiome—two important factors in maintaining a healthy weight.*

Berberine has also been clinically validated to help lower total cholesterol, particularly the less favorable LDL type, and is effective in supporting healthy lipid levels. The patented berberine extract found in Bizorn BERBERINE was shown in a clinical trial to lower total cholesterol by 8% in just 60 days.*

For more targeted support for cholesterol balance, we recommend you try our Bizorn HEART formula, which can be taken together with Bizorn BERBERINE.*

Berbevis® Berberine Extract (1,100 mg)
Bizorn BERBERINE is made with Berbevis®, a patented, clinically studied, standardized phytosome-form berberine extract that is clinically proven to significantly reduce insulin resistance within just 30 days while reducing visceral fat by 22% on average within 60 days. Visceral fat, which surrounds your organs, is considered the most dangerous kind of fat.*

While typical berberine extracts are notoriously difficult for the body to absorb, Berbevis® solves this problem with a next-generation phytosome delivery system that offers 10x better absorption compared to other berberine supplements.*

In a landmark 60-day study Berbevis®:

• Slashed fasting insulin levels by 42%*
• Reduced HOMA score (a measure of insulin resistance) by 49%*
• Decreased fasting blood sugar by 12%*
• Reduced visceral fat by 22%*
Another study, a randomized, double-blind, placebo-controlled clinical trial produced similar results, with Berbevis® normalizing fasting blood sugar and moving subjects out of “danger zone” classification within 60 days. It also decreased visceral fat, reduced body fat mass, shrunk waistlines and lowered total cholesterol by 8%. No other berberine supplement has produced these impressive results.*

Greenselect® Green Tea Extract (300 mg)
Greenselect® is a patented, decaffeinated green tea extract shown in clinical trials to support weight loss of up to 30 pounds in 90 days when combined with a reduced calorie diet.*

Green tea polyphenols, particularly catechins such as epigallocatechin gallate (EGCG), have been extensively studied for their health benefits, including their role in supporting weight loss. Greenselect® combines green tea polyphenols with phospholipids in a phytosome delivery system to improve their absorption and bioavailability. Greenselect® offers a 2-fold increase in absorption and a 20% increase in plasma antioxidant potential compared to standard green tea extract.*

Greenselect® provides safe and extremely effective natural support for weight loss by stimulating thermogenesis (the process by which the body generates heat and energy from metabolism of food) and fat oxidation (the process of breaking down fat into energy). It also helps regulate appetite and promotes feelings of satiety, helping to prevent overeating.*

In one study, Greenselect® helped a group of men and women lose an average of 13.23 pounds in 45 days, and an average of 30.86 pounds in 90 days. This remarkable weight loss was accompanied with a 12% reduction in body mass index (BMI) after 90 days.*

Another clinical trial showed a 13.9% reduction in BMI, a 10.7% reduction in waistline for men, a 9.1% reduction in waistline for women and 7.1% reduction in fasting glucose all around.*

Albion® Chromium (200 mcg)
Bizorn BERBERINE features top-of-the-line Albion® chromium. This patented, chelated (amino acid-bound) form of chromium offers superior absorption, blood sugar balancing benefits and fat loss support.*

Chromium is an essential trace mineral that plays a crucial role in blood sugar metabolism, the body's ability to process and utilize sugar from the bloodstream for energy. It helps maintain blood sugar balance, which is a critical factor in reducing fat storage. Studies have shown that chromium can help increase lean body mass while decreasing body fat percentage.*

Chromium can also help fight cravings that can derail your weight loss plan. Some research suggests that chromium supplementation helps reduce cravings for carbohydrates and sweets by influencing neurotransmitters involved in appetite regulation.*

Why We Use Amber Glass Bottles vs. Clear Glass or Plastic
• Glass is infinitely recyclable and reusable.
• Protects the ingredients from UV light damage.
• No risk of chemicals in plastics leaching into pills.

We all want to age well—andlive wellfor as long as possible. And while there are many factors that contribute to healthy aging and longevity, scientists are beginning to understand some key cellular mechanisms that influence how we age. Nearly all of the common complaints we associate with aging, from joint pain, fatigue and brain fog to declining vision and wrinkles, are a result of our cells getting worn out and damaged over time.*

The great news is cutting-edge research is revealing that we have some control over our cellular aging process—and that key antioxidants and inflammation fighters can play a major role in making our cells biologically younger.*

That’s why Dr. Passero formulated Bizorn LONGEVITY, drawing on over 20 years of clinical experience and research, with two natural, plant-based compounds shown to be among the most effective on earth for combatting cellular aging—Zanthin® astaxanthin and Pomella® pomegranate extract. These multifunctional antioxidants target the fundamental causes of aging, rejuvenating cells and helping you look and feel younger, longer.*

Zanthin® Astaxanthin (12 mg): A Triple-Strength Dose of Nature’s Most Potent Multifunctional AntioxidantZanthin® astaxanthin is the finest, highest quality form of astaxanthin on the planet. Naturally sourced exclusively from microalgae grown in a remote, pristine, controlled environment in Chile, Zanthin® is extracted in the USA without solvents or harmful chemicals using a Deep Extract® high pressure supercritical CO2 extraction process and Peroxidation Blocker Stabilization technology (O2B®) to ensure the utmost purity and potency.*

While many supplements only have 4 mg of generic (and often synthetic) astaxanthin that provides far less health benefits, Bizorn LOVGEVITY features a triple-strength 12 mg dose of Zanthin® based on the dozens of studies that demonstrate astaxanthin’s benefits are the most profound at this level.*

Astaxanthin is widely considered nature’s most powerful antioxidant. It was shown in recent groundbreaking NIH-funded research toextend lifespan in mammals by up to 12%, which equates to 9+ years.The results of this important study, conducted as part of the Interventions Testing Program (ITP) supported by NIH’s National Institute on Aging, singled out astaxanthin as one of only a few compounds on earth scientifically proven to significantly extend lifespan.*

The ITP examines the impact of anti-aging compounds on lifespan and is widely recognized as the gold standard in longevity research. Since longevity is difficult to study in humans because of our long lifespans, the researchers start by testing the anti-aging compound on fruit flies and other very short-lived invertebrates, and if the data is promising, they move to study it in mice or other mammals. Astaxanthin is the first compound in the ITP’s 20-year history shown to yield more than a 10% increase in mammalian lifespan that is also considered exceptionally safe for daily use.*

Additional studies have shown that astaxanthin “switches on” both Nfr2 and FOX03, two gene activators closely linked to longevity and protection against aging in humans.*

The secret to astaxanthin's effectiveness may lie in its unique molecular structure, which is identical to that of the human cell membrane. This allows it to span the entire cell membrane, simultaneously providing protection in both the inner and outer regions of the cell. No other antioxidant has this capability, allowing astaxanthin go where other antioxidants can’t to mount a powerful defense against oxidative stress, DNA damage and inflammation—keys to maintaining healthy, resilient, biologically younger cells.*

Numerous clinical studies have shown that these cellular benefits translate intopowerful anti-aging support and protection for your heart, brain, eyes, skin and more. In addition, Zanthin® astaxanthin can help you stay active, thanks to its proven ability toimprove joint comfort, muscle endurance, exercise performance and post-workout recovery.*

At the 12 mg dose, which is three times the amount found in typical supplements, Zanthin® astaxanthin has been scientifically proven to:

1. Combat Oxidative Stress from Reactive Oxygen Species:Oxidative stress leads to a cascade of cellular damage, including damage to DNA and mitochondria, that leads to body-wide inflammation, contributing to various age-related conditions. Clinical research has demonstrated that Zanthin® astaxanthin possesses up to6,000 times the free radical neutralizing power of other well-known antioxidants.*

2. Neutralize DNA Damage:Caused by oxidative stress, DNA damage can accelerate aging. A 2010 study showed that Zanthin® astaxanthinprevented the progression of cellular DNA damage within four weekswhile reducing inflammation, with effects confirmed again at eight weeks.*

3. Reduce Body-Wide Inflammation:Age-related inflammation driven by oxidative stress, often referred to asinflamm-aging, has been linked to numerous health issues and is considered a major driver of the aging process itself. A 2016 study indicated that Zanthin® astaxanthin downregulated pro-inflammatory cytokines and upregulated anti-inflammatory cytokines, resulting in a significantly reduced inflammatory response. Astaxanthin also acts as an immunomodulator, ensuring a proper immune response to manage inflammation.*

Pomella® Pomegranate Extract (300 mg): Proven to Boost Levels of Cell-Energizing Urolithin AWhile astaxanthin provides extraordinarily powerful support for cellular rejuvenation and healthy, resilient aging, there’s another antioxidant-packed ingredient emerging from the research that provides a unique and exciting anti-aging benefit Dr. Passero wanted to harness.*

Derived from pomegranate, a fruit known for its longevity-enhancing benefits since ancient times, Pomella® is a proprietary, clinically studied whole fruit pomegranate extract standardized to provide 30% punicalagins, a unique type of antioxidant polyphenol classified as an ellagitannin and known to offer powerful health benefits. This is a much higher level than what pomegranate juice and other extracts provide, helping to overcome the absorption issues associated with ellagitannins to ensure maximum efficacy.*

Also unlike pomegranate juice and many pomegranate extracts, Pomella® captures the full antioxidant profile found naturally in whole pomegranate fruits—including the peel, pith and seeds. And it’sthe only pomegranate extract clinically proven to boost levels of urolithin A—a rare cell-energizing compound produced in the gut through the metabolism of pomegranate’s punicalagins. In this way, Pomella® also acts as a prebiotic, enhancing gut microbiome health and gut barrier function.*

Urolithin A is a revolutionary anti-aging compound thattriggers mitophagy, a crucial process that cleans up dysfunctional mitochondria and helps them repair and recycle themselves, optimizing mitochondrial function. Healthy mitochondria are essential for cellular energy production, and their optimal function is key to resilience, energy, strength and longevity.*

Clinical research has shown that urolithin Aboosts energy and significantly improves muscle functionin middle-aged and older adults. It has also been shown to extend lifespan while enhancing cognitive health. Researchers believe that urolithin A, along with the other beneficial punicalagins found in pomegranate, may be able to activate critical antioxidant enzymes in the body, and recent research on Pomella® confirms this theory.*

A randomized, double-blind, placebo-controlled, parallel trial found that a 300 mg daily dose of Pomella® yielded the following improvements in antioxidant status:

• Total antioxidant activity increased by 379%*
• Superoxide dismutase (SOD), an enzyme that protects cells from oxidative stress, increased by 149%*
• Glutathione peroxidase, the enzyme responsible for making glutathione, the body's master antioxidant) increased by 230%*
• Glutathione reductase, the enzyme that activates glutathione, increased by 163%*

Pomella®, at a dose of 300 mg per day, is also clinically proven tosignificantly reduce the appearance of fine lines and wrinkles within just 4 weeks.Researchers believe Pomella®’s remarkable anti-aging skin health benefits may be tied to its beneficial impact on the gut and skin microbiomes and ability to prevent the breakdown of collagen fibers in the skin.*

Other research focused on pomegranate’s well-known heart health benefits demonstrated that Pomella® decreased total and LDL cholesterol levels while improving HDL (good) cholesterol functionality and other parameters of cardiovascular health.*

Pomella® is fully traceable to orchards in India, where pomegranates are sustainably grown to maximize quality and polyphenol content. It is Certified Glyphosate Residue-Free and Non-GMO Project Verified.*

Dr. Passero says this is one supplement he takes each and every day to support cellular rejuvenation, resilient aging, and overall health and longevity. If you’re looking to optimize your cellular health and effectively slow down the aging process, you’ll find the antioxidant firepower you need in Bizorn LONGEVITY’s unique and potent combination of Zanthin® astaxanthin and Pomella® pomegranate extract.*

Why We Use Amber Glass Bottles vs. Clear Glass or Plastic

• Glass is infinitely recyclable and reusable.
• Protects the ingredients from UV light damage.
• No risk of chemicals in plastics leaching into pills.